Labdane is a natural bicyclic diterpene. It forms the structural core for a wide variety of natural products collectively known as labdanes or labdane diterpenes. The labdanes were so named because the first members of the class were originally obtained from labdanum, a resin derived from the gum rockrose.

A variety of biological activities have been determined for labdane diterpenes including antibacterial, antifungal, antiprotozoal, and anti-inflammatory activities.

Example labdane derivatives

  • Forskolin
  • Galanolactone
  • Isocupressic acid - is an abortifacient component of Cupressus macrocarpa.
  • Medigenin
  • Sclareol
  • Stemodene

See also

  • Abietane

References


Figure 1 from Isolation of a New Diterpene from Vitex

Cytotoxic activities of diterpenes from the Zingiberaceae

Chemical structure of the labdane diterpenes. Chemical structures of

Chemical structure of the labdane diterpenes. Chemical structures of

Chemical structures of several labdane acids. Download Scientific Diagram